Volume4

Introduction: Midfoot injuries are highly uncommon injuries, often due to high-energy trauma. The purpose of the study is to evaluate the functional outcomes of various modalities of treatment of midfoot injuries.
Methods: Prospective single centre study, conducted for a period of 24 months in a rural secondary level hospital, which included 40 patients aged between 18 and 62 years, with midfoot injuries. Final outcome analysis included demographic, injury and treatment characteristics.

Introduction: Inferior turbinate hypertrophy is one of the most common cause for Chronic nasal obstruction, which sometimes do not respond to medical management and needs surgical correction. The basic principle of surgical correction is to reduce the symptoms and preserve the functional anatomy of nasal airway.
Aim & objectives: To compare the efficacy of partial inferior turbinectomy(PIT) and submucosal diathermy(SMD) in terms of intra operative and post-operative bleeding, healing, post-operative nasal patency improvement

The cerebral palsy is the most frequent permanent physical disability of childhood. Its incidence is estimated to be 3.3 / 1000 live birth. 10% of infants have neurologic defects. The incidence of cerebral palsy among all premature infant varies but approximately 5 to 10 %. Feeding problems are quite common in children cerebral palsy (CP). 30 to 80% of disabled individuals feed with difficulty. They are especially at risk because of oral, pharyngeal or oesophageal dysphagia and due to oral motor dysfunction (OMD).

The characterization of chemical constituents of alcohol-water extracts of Parkia biglobosa and Spondias mombin leaves revealed the presence of the following two important chemical groups: catechical tannins, reducing compounds and mucilage. Gallic tannins, flavonoids, leucoanthocyans, combined anthracenic derivatives (C-Heterosids), coumarin are found only in Parkia biglobosa leaves and saponosids are present only in Spondias mombin leaves.

Amphotericin B (AmB) is an important antibiotic agent; however, nephrotoxicity is one of the main adverse effects. The purpose of this study was to evaluate the effect of cAMP and cGMP in nephrotoxicity caused by AmB from the assessment of cytokines, stress oxidative, nitric oxide production and cell death in MDCK cells line. Our results showed an increase of IL-6 production by AmB, and an inhibitory effect was observed when cells were incubated with AmB plus cAMP. Results with TNF-α showed that cAMP is able to produce TNF-α only up to the basal level similar to AmB.

Background: Various neurological manifestations of pediatric systemic lupus erythematosus (pSLE) have been reported. However, Guillain-Barré syndrome (GBS) as the initial presentation has rarely been documented. We report a case of the acute motor axonal neuropathy (AMAN) subtype of GBS as the first presentation of pSLE.

Cystic fibrosis is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms.

Introduction: Diabetes mellitus (DM) patients with dyslipidemia are soft targets of cardiovascular deaths. Very few studies have previously tried to find correlation between HbA1c levels and lipid profile. In present study primary objective was compare dyslipidaemia between good glycemic control and poor glycemic control groups whereas secondary objective was to find correlation between fasting serum glucose (FBS), two hours post prandial serum glucose (PPBS) and HbA1c and serum lipid profile in type 2 DM patients.

Sarpagandha (Rauwolfia serpentina) is one of the most popular Vedic medicinal herbs used from 1000 BC to till date for reducing high blood pressure related ailments. It’s a long journey of Sarpagandha from British India to the Western communities. Last 75 years intensive knowledge on Sarpagandha confirmed reserpine, an indole alkaloid is the most responsible component for its bioactivities. Reserpine also reported for severe adverse reactions, if not properly used. After that, several attempts were made to identify reserpine in formulations.

Objective: The purpose of the study was to determine the various bacteria etiologies inciting urinary tract infections and their antimicrobial susceptibility at a tertiary care centre in North India.