Volume4

A study to assess the effectiveness of structured teaching programme on knowledge and practice regarding endotracheal suctioning among staff nurses in intensive care units of selected hospitals in kollam

Subject: A study to assess the effectiveness of structured teaching programme on knowledge and practice regarding endotracheal suctioning among staff nurses in intensive care units of selected hospitals in Kollam.

Postpartum depression

Postpartum depression affects up to 15% of mothers. recents research has identified several psychosocial and biological risk factors of postpartum depression.symptoms are might show any time within first year. treatment recommendation include psychotherapy and antidepressant medication. further systematically the short-term and long-term effect of medication exposure through breastmilk on infant and child development.

Evaluation of renal function by pre and post-operative radiological and biochemical investigations in patients of obstructive uropathy due to urinary stones

Urolithiasis has affected the mankind for long years and these stones have caused progressive renal impairment. These patients usually present with characteristic loin pain, vomiting, sometimes fever, some patients may also be asymptomatic at times. Urinary calculi may cause various complications like obstruction, infection and renal failure. Obstructive uropathy refers to the structural impedance to the flow of urine anywhere along the urinary tract leading to hydronephrosis.

Immunohistochemical study of hormonal receptors in endometrium of women with dysfunctional uterine bleeding: a prospective cross-sectional study at a tertiary center

Dysfunctional uterine bleeding is a major gynecologic problem, with varied treatment options. A significant proportion of these patients undergo hysterectomy. To investigate the hormonal milieu at tissue level, we semi-quantitatively assessed the estrogen and progesterone receptors in the endometrial samples of 50 DUB patients, by Immunohistochemistry.

Sirtuin1: serendipitous and enigmatic molecule

Biological marker or biomarker is an indicator of physiological or pathological changes in an organism. A biomarker is valid only after evaluation and approval by Food and Drug Administration (FDA) committee. Three step evaluation processes for biomarker includes: Validation, Qualification and Utilization. Present review highlights recent trends of biomarker in Diabetes and diabetic nephropathy and an emerging protein a natural boon for life: the Sirtuin.

Complementary alternative medicine use among patients with diabetes coming to the geriatric clinic at tertiary care hospital in chandigarh, india

Introduction: Complementary alternative medicine (CAM) is increasingly used throughout the world, especially among individuals with chronic illnesses such as Type 2 Diabetes Mellitus (T2DM). This study was done with an objective to findthe prevalence, types, and reasons for CAM use among patients with diabetes in northern India. Methods: The cross-sectional study was conducted over a period of six months (September 2016 to February 2017) among patients with diabetes coming to the geriatric clinic at a tertiary care hospital in Chandigarh, India.

Safety of a drug beyond molecule: what we have learned from recall of valsartan

Valsartan was a world’s number one selling high blood pressure drug .The patents for valsartan and valsartan/hydrochlorothiazide expired in September 2012. The drug is a very good target for the generic industries after patent expiry. However, in July 2018 Drug was recalled due to impurities by various countries including USA and Europe. This recall was due to an impurity, N-nitrosodimethylamine (NDMA), which was found in the recalled products. Later on during review another compound N-nitrosodiethylamine (NDEA) discovered in losartan.

Co-relation between fractures of the mandibular angle with the presence or absence of impacted third molar - a retrospective and radiographic analysis

Aims and Objectives:
1. To evaluate the co-relation between fractures of the mandibular angle with the presence or absence of impacted third molars.
2. To assess the influence of the angulation, position and degree of impacted third molars on the incidence of mandibular angle fractures.
3. To determine the necessity of prophylactic removal of impacted mandibular third molars.
4. To correlate the site of fracture with the age, sex and the cause of injury.

Alcoholism and treatment modalities

Alcohol may be the most widely used drug in human history. It has been consumed for millennia world wide for religious, cultural act ivies and celebrations. Alcoholism is the most severe form of alcohol abuse.  Long-term use of alcohol can damage every single organ in the body as well as emotional and mental health, financial status, employment, and social interactions.