Volume7

A clinical endocrinological quantitative study of specific symptomatic features among global type ii diabetic patients and a pharmacogenomic analysis of anti-diabetic pharmacotherapeutic agents

Introduction: The heterogeneity of type II diabetes mellitus manifestations depends on the subgroups of diabetes, the clinical variables, disease progression, genetic makeup and lifestyle factors; and this determines the response to treatment with novel glucose-lowering drugs, and lifestyle modifications
Objectives: The objective of this study is a clinical endocrinological quantitative analysis of specific symptomatic features among global type II diabetic patients, and a pharmacogenomic analysis of anti-diabetic pharmacotherapeutic agents.

Case report: a 22 year old female presenting with hypokalemic paralysis in newly diagnosed gitelman syndrome

Introduction: Gitelman syndrome (GS) is a rare, salt-losing tubulopathy characterized by hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria. The disease is recessively inherited, caused by inactivating mutations in the SLC12A3 gene that encodes the thiazide-sensitive sodium-chloride cotransporter (NCC). GS is usually detected during adolescence or adulthood, either fortuitously or in association with mild or nonspecific symptoms or both.

Mortality analysis of covid 19 cases at a tertiary care centre in western maharashtra

COVID 19 disease emerged in Wuhan, China and spread like a storm throughout the world including India. Mortality due to covid was of high concern during the pandemic.
Aim: The study was designed to analyze the various parameters in covid 19 non survivors and their correlation with mortality at a tertiary care hospital.

Challenges in the management of addison’s disease-a case study report

Addison’s disease is a rare endocrine condition due to adrenal insufficiency which results in severe weight loss. The main objective of the study is to investigate the diagnosis and treatment of Addison’s disease. A 35-year-old female presented to the hospital with fever, generalized weakness and blisters all over the body. She had known history of epilepsy and was in coma for 13 days in 2013. Nutritional screening was done in which there was weight loss, loss of appetite and decreased intake. Scores obtained from PGSGA and NRS 2000 depicts that the patient is nutritionally at risk.

Prevalence of subclinical hypothyroidism in hiv/aids patients – a cross sectional study

Background –Prevalence of overt thyroid disease in human immunodeficiency virus (HIV) infected or acquired immunodeficiency syndrome (AIDS) patients is apparently similar to general population. Subclinical hypothyroidism is reportedly more common in HIV/AIDS patients. This issue is being explored in the present study. Aim and Objective -To assess the prevalence of clinical and subclinical thyroid dysfunction in HIV/AIDS patients. Materials and methods –It is a cross sectional study conducted on 150 HIV/AIDS patients.

To study causes and visual outcomes in patients with penetrating ocular injuries

Aims and objectives 1. To study causes of penetrating ocular injuries. 2. To study demographic profile of patients presenting with penetrating ocular injuries. 3. To study type of clinical presentations of penetrating ocular injuries.. 4. To study visual outcomes and prognostic factors affecting visual outcomes in penetrating ocular injuries. Method: Study included30 Patients. A detailed history was taken regarding preliminary data like age, sex, occupation time of injury, object causing injury, cause of injury.

The quality of life of health colleges students studying atking faisal university in al-ahsa, eastern province, saudi arabia

Introduction: Poor Quality of Life (QOL) among medical and health students is related to an unhealthy lifestyle, psychological distress, and even academic failure that could affect their care for patients in the future. Material and Methods: This cross-sectional study was conducted among King Faisal University (KFU) students, particularly health college students, to evaluate their QOL using the Arabic version of the WHOQOL-BREF instrument for data collection. Results: A total of 346 students were included with a mean age of (21.4 ± 1.88) years.

A case control study on expression of cyclin d1, p16 and retinoblastoma protein in carcinoma of the gall bladder

Background: Carcinoma of the gall bladder is a highly malignant tumor, with poor prognosis except when incidentally diagnosed at an early stage after cholecystectomy for illness other than carcinoma. The incidence of carcinoma of the gall bladder varies considerably in different parts of the world. A large number of risk factors have been proposed in the etiopathogenesis of carcinoma of the gallbladder. Cholelithiasis with or without chronic cholecystitis has been on the top among these causes.

Thrombolysis in wake-up acute ischemic stroke

Wake-up acute ischemic stroke is medical emergencies as in reality there is a narrow window for acute reperfusion therapy with iv thrombolysis in this group. There is a significant amount of patients who presents with wake-up acute ischemic stroke reaching around 30%. If no appropriate diagnostic tools are used clinician is likely to miss opportunities for IV thrombolysis leading to increased morbidity leading to acute stroke patients.

Outcome of postdated pregnancy in a teaching hospital of kolkata, india during covid pandemic

Background: The risks to the fetus increase after 41 weeks mainly due to increasing fetal weight, decline in placental function, oligohydramnios which increase chances of cord compression, and meconium aspiration. Perinatal mortality after 42 weeks is twice as compared to the perinatal mortality at 40 weeks and by 44 weeks the rate is increased up to threefold. In cases of prolonged pregnancy, fetus is more at risk of hypoxia during labor than a fetus at term.