Is covid vaccine immunity success story gives “a lot of happy tears”?

Author: 
Raghavendra Rao, MM Karindas, Ilie Vasiliev, Chennamchetty Vijay Kumar4 Hitesh Lakshmi Billa, Dilip Mathai, Manick Dass and Mahendra Kumar Verma

Acquiring vaccinated could rescue your life. COVID-19 vaccines furnish powerful protection against grave illness, hospitalization and death. The SARS-CoV-2 pandemic is now better controlled in background with entry to fast and reliable testing and highly effective vaccination
Eradication of coronavirus disease 2019 (COVID-19) appears practically impossible, as already spread globally to several million people. There is an urgent need to improve, appreciate and comprehend the knowledge of the immunology of this disease by developing vaccines and medicines for the prevention and treatment of patient. Viruses are obligate intracellular parasites require their host to replicate them and propagate. Respiratory viruses cause serious emerging infectious diseases. Not only the disastrous original influenza viruses, SARS, MERS, or COVID-19, but seasonal influenza viruses regularly lead to serious morbidity and mortality. Many viruses infect humans and most are regulated by the immune system with controlled injury to host tissues. Some viruses, however, do cause damage to the host. These viral antigens can be either approved by the B cells or presented by MHC complexes to the T cells, resulting in antibody production, elevated cytokine production, and cytolytic activity in the acute phase of infection. Contaminated humans can, after convalescence, produce aggressive defensive responses by generating a memory T-cell pool against SARS-CoV and MERS-CoV. Memory T cells were not constant in the long term and, upon reactivation, became local harm due to cross-reactivity.

Page: 
294-300
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DOI: 
http://dx.doi.org/10.24327/23956429.ijcmpr20220069
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