The human cytomegalovirus (CMV) is widely distributed among the human population as one of the most common causes of congenital infections. Congenital CMV infection is seen inapproximately 1% of all newborns of which 10% are symptomatic at birth and is a leading cause of sensorineural hearing loss, vision impairment, varying degrees of intellectual disability and delayed psychomotor development. Here, we present the case of a 7-month-old male child with symptomatic congenital CMV infection presenting as interstitial pneumonitis. Congenital CMV infection was confirmed by Urine PCR and supported by serology, MRI Brain, BERA, fundus examination and clinical history. Associated findings include SGA, microcephaly, severebilateral sensorineural hearing loss, chorioretinitis, periventricular leukomalacia, persistent lymphocytosis and failure to thrive. Marked improvement in signs and symptoms was observed after treatment with Valganciclovir was initiated according to protocol.
