Volume8

Dexmedetomidine is a potent highly selective α-2 adrenergic agonist acts centrally, also possesses synergistic action with local anaesthetics is a commonly used adjuvant for regional and neuraxial blocks, used as anxiolytic, sympatholytic, hypnotic, sedative, and analgesic properties without generating significant respiratory depression. To compare the post-operative analgesia, hemodynamic changes produced by epidural injection ropivacaine (0.2%) against ropivacaine (0.2%) with dexmedetomidine (1mcg/kg) in patients undergoing open abdominal surgeries.

A Comparative study of intrathecal 1% Chlorprocaine and 0.5% Ropivacaine in perianal surgeries. To compare the time of onset, height of block, intensity of sensory and motor blockade, duration of analgesia, time to ambulation, time to discharge as well as the incidence of side effects between the two groups.

Background: Organophosphorus (OP) compound poisoning is one amongst the foremost common poisonings in India because of easy availability, often requiring ICU care and ventilatory support. Clinical research has shown that respiratory failure is the most important cause of death due to Organophosphorus poisoning. This hospital-based, observational study is taken up as an attempt to know the clinical and biochemical factors like serum pseudo cholinesterase levels which can predict the timely need for ventilator support.

Introduction: Prostate gland specimens account for the significant percentage of diagnostically challenging cases in surgical pathology practice. Benign prostatic hyperplasia is an extremely common condition in men over the age of 50 yrs. In India prostate cancers constitute about 5% of all cancers in male. Aims and Objectives:1) To estimate the various histopathological pattern of prostatic lesion.2) To estimate the occurrence of benign prostatic hyperplasia, prostatitis, type of carcinoma.

Background: The Valsalva maneuver is commonly performed during everyday activities such as lifting, defecation and coughing, and is characterized by changes in intrathoracic pressure that have a pronounced effect on venous return, cardiac output and blood pressures. purpose of this study was to examine the cerebral hemodynamic response to graded valsalva maneuver
Objectives: To assess cerebral hemodynamics during graded valsalva maneuvers study in 80 young healthy females using transcranial haemodynamics.

Clinical practice and clinical research is a collaborative platform for advancing scientific developments in the field of medical education. Research, education and clinical practice are associations for pooling knowledge in the discipline of evidence based medicine for taking forward the complex challenges of diseases and disrupted pathologies.

The molecular properties and the bio-activity score of 2-(2-methyl-4-oxoquinazolin-3(4H)-yl)-N'-[(E)-(substitutedphenyl)methylidene]acetohydrazidewere calculated by usingmolinspiration software. These compounds have miLogP values in the region of<5indicating that they have moderately permeability through cell membranes. TPSA between 76.36 to 122.18 (far below 160) and a molecular mass of less than <500.

The establishment of the so-called Sansha city and related acts have seriously violated Vietnam's sovereignty over the two archipelagos of Hoang Sa and Truong Sa and are therefore invalid and unsuitable. Never recognized by the international community. Over the past 10 years, China has made every effort to foster and reinforce illegal fallacies about the legal status of this Sansha city.

Background: TB and mental illness often co-exist and though causality has not been established, mental illness has found to be significantly affect the outcome.
Objective: To study the prevalence of depression and their causes in tubercular patients who are on treatment.

Introduction: Recovery of Patients of Severe Acute Malnutrition (SAM) after discharge from Nutrition Rehabilitation Centre (NRC) is unsatisfactory on Home-based diet. Authors, therefore, compared recovery of children with SAM on discharge between patients given home-based diet with those given Local Therapeutic Feed (LTF) in addition to home-based diet
Aim: To compare weight gain between SAM children on discharge from NRC taking non-milk based LTF with home- based diet with those taking only home-based diet