Saffron is a medically famous and important spice, derived from the flower of Crocus sativus, commonly known as the "saffron crocus". it belongs to the Genus Crocus, Order Lilacs, and Family Iridaceae. There won’t be any place in the world, that won’t be familiar with saffron, including Afghanistan too. The original way to obtain saffron is the stigma and styles, collected and dried for use mainly as a seasoning and coloring agent in food. The three crimson stigmas of it are the most valuable part of the plant. Saffron as a medicinal plant has many therapeutic effects. saffron is composed of at least four active phytochemicals which include crocin, crocetin, picrocrocin, and safranal. pharmacological effects such as anticonvulsant, antidepressant, anti-inflammatory, antitumor, radical scavenger effects, learning, and memory-improving effects, etc... this cross-sectional research is applied to saffron samples in the Kabul city. The results of organoleptic studies and chemical tests were obtained by examination of fifty saffron samples that are founded 4% adulteration.