2016 WHO Classification of lymphoid neoplasm has included Angioimmunoblastic T Cell Lymphoma (AITL) under the umbrella of nodal T-cell lymphoma that also include follicular T cell lymphoma and peripheral T cell lymphoma, not otherwise specified. AITL represents only 1-2% of all non hodgkin’s lymphoma. A 27years old male presented with fever, pruritus and generalized lymphadenopathy. A lymph node biopsy showed the characteristic histological and immune-profile consistent with AITL. The patient received two cycles of CHOP and accomplished complete remission. A follow up period of 5 years showed recurrence free survival. The case highlights the characteristic histology and immune-profile of this rare entity of lymphoma with a particular emphasis on the efficacy of CHOP in achieving complete remission.
