Epilepsy is one of the most common brain disorder which compromises the patient’s quality of life. Even many old and new antiepileptic drugs are available, treatment of epilepsy is far away from achieving optimum results. In the etiopathogenesis of epilepsy recently, the role of oxidative stress and inflammation is highlighted. Certain antiepileptic drugs like sodium valproate, phenytoin sodium and carbamazepine were found to either initiate or enhance the oxidative stress and weaken the antioxidant defense mechanism. They also have serious adverse reactions including teratogenicity. Hence there is a serious need of searching newer drugs which will address the problems of the inflammation and oxidative stress efficiently. Ginger was proved to overcome these problems effectively and adequately. Ginger is devoid of any serious adverse effects of antiepileptic drugs including teratogenicity and fills the void of safe and effective adjunct in the treatment of epilepsy. After conducting extensive clinical trials, it’s regular use can be encouraged in the treatment of epilepsy to achieve the satisfactory control of epilepsy.
