An overview on therapeutic role of combination of probiotics in treating peptic ulcer

Peptic ulcer is a chronic gastrointestinal disorder characterised by localised erosion in the stomach lining those results in to abdominal pain, hyper acidity, bleeding, nausea, bloating or diarrhoea. The most common cause of peptic ulcer is infection due to Helicobacter pylori or prolonged use of Non-Steroidal Anti-Inflammatory (NSAID) drugs. This review aims to provide an overview on the combination of different strands of Lactic Acid Bacteria (LAB) and bifidobacterial involving mechanisms that protects the gastric mucosal layer, helps in upregulation of prostaglandin for improving stomach lining, anti-inflammatory property of probiotics in peptic ulcer caused due to pro-inflammatory cytokines.