Twelve years experience in management of perforated peptic ulcer in university hospital of marrakech about 1024 cases

Background: the incidence of PPU has remained constant, simple closure being the mainstay treatment.
Objective: we present in this work the experience of our service in management of perforated peptic ulcer, specifying the epidemiological, clinical, therapeutic and evolutionary aspect
Materials and methods: this was a retrospective study of patients who underwent emergency surgery for PUP between January 2004 to December 2015, the patients bio-data, clinical, operative findings and treatment outcome were extracted and analyzed , all the cases of generalized peritonitis not traceable to peptic ulcer perforation were excluded from the study.
Results: A total of 1024 patients were included in this retrospective study , 1003 males and 21 females, their ages ranged from 12 to 80 years ,with a mean of 37.5 years ,common risk factors were smoking (81.44%),history of peptic ulcer disease(9.57%) and use of NSAIDs (6,54%), a significantly increased risk of perforation was evident during the daytime fasting month of ramadan, simple closure of the perforation was the most common procedure performed, median length of stay was 6 days , mortality and morbidity rates were 0.69%, 6.55% respectively.
Conclusions: PUP is a serious condition, requiring emergency surgical management, simple closure of the perforation was the most common procedure performed in ours series.