Introduction: Hypertension is an major health related risk factor in India with major contribution to burden of disease and mortality .It contributes to 1.6 million deaths annually in India due to ischemic heart disease and stroke. 57% of deaths related to stroke and 24% of death are related to hypertension. Hypertension is one of the commonest non communicable disease in India with an overall prevalence of 29.8% with a higher prevalence in urban areas. Although our understanding of pathophysiology of hypertension has increased, etiology remains hypothetical . Various studies have shown that essential hypertension is associated with disturbed calcium metabolism like increased cytosolic calcium and decreased serum calcium levels and also increased urinary excretion of calcium in patients with essential hypertension. In this study total serum calcium and corrected serum calcium levels of essential hypertension patients are compared with total and corrected serum calcium of matched normotensive controls.
Aim of the Study: 1. To study the total and corrected serum calcium levels between patients with essential hypertension and normotensive controls.
Materials and Methods: The work was carried out in the out patient department and medical wards of Rajah Muthiah Medical College Hospital, Chidambaram. During October. 2016 to August 2018 it is an cross sectional study with sample size of 100 with 50 newly diagnosed essential hypertension and 50 matched normotensive controls. The present project was approved by the ethical committee
Results: The mean total serum calcium and corrected serum calcium levels in hypertensive patients were comparatively lower than the normotensive group.
Conclusion: There was a negative correlation noted between the total and corrected serum calcium levels in the hypertensive patients. The calcium levels were significantly lower in the hypertensive group
