This present paper enlightens the establishment of resemblance between the Agya Chakra and its petals with the modern neuro-anatomy. The Chakras are vortices of Pranic energy at specific areas in the body which manage the transmission of Prana (energy) permeating the intact human structures and physiology. Activation of the Chakra through various Yogic practices regulates all the psycho physiological functions. The Chakras represent various neuronal plexuses and sub plexuses which are related to particular viscera and its physiological functions. Based on the position, structure and various functions described by Acharya and scholars it can be concluded that hypothalamus nucleus and its plexus resemble with the Agya Chakra (presents in between the two eyebrows). A cadaveric study was carried out to correlate and ascertain that the anatomical structures which closely resemble the Agya Chakra can be thought of as hypothalamus, its nuclei and associated neuronal plexuses.
