Comparison of substantivity of anticariogenic property of polyphenol extract from cranberry with 0.2% chlorhexidine mouth wash

Aim: The aim of the study is to determine the duration of antibacterial substantivity of polyphenol extract mouth wash after a single oral rinse and to compare it with the substantivity of 0.2% chlorhexidine (CHX).
Materials and Methods: In this study, unstimulated saliva from thirty individuals was colected 2 hours after usual oral hygiene procedures but not rinsing (pre-sample) with randomly selected mouthwash, (10% polyphenol extract from cranberry mouthwash, 0.2% chx, and normal saline) and 5 min after rinsing (postsample). A washout period of 1 week was kept between two rinses. The sampling was replicated after every 2 hour for 12 hour (post 1, post 2, post 3, post 4, post 5, and post 6) and was tested for microbial count.
Statistical Analysis Used: Friedman test, Kruskal–Wallis test, and post hoc analysis were used to evaluate the outcome of sample mouthrinses on CFUs at different times.
Results: Polyphenol extract showed statistically significant results when the antibacterial effect at post, post sample 1 and post sample 2 were compared to pre-sample count (P < 0.05). After which the effeciancy declined and was equal to normal saline (P > 0.05). The results for Chlorhexidine were statistically significant at all times when compared to pre-sample count (P < 0.05) and it revealed the maximum substantivity of 7 hours.
Conclusion: After a rinse with normal diet without restrictions over the day, polyphenol extract mouthwash had an antibacterial effect for 3–4 hours. It can be used three times daily for its maximum antibacterial effect.