Objectives: Most hospitalized ill patients have wasting syndromes, especially kwashiorkor which characterized by hypercatabolic status.Ideally, enteral nutritional formulas (ENFs) nutritional intake should be taken orally or enterally through various feeding tubes at least at trophic feeding (TF) dose (10-20 ml/hr) to maintain the integrity of enterocytes and subsequently to mitigate bacterial translocation.In our study, we evaluated the clinical and economic impacts of using supplemental six ENFsthat were available in our institutional at TF dosefor at least 1 week in total parenteral nutrition (TPN) dependent patients.Methods: Our study was retrospectively conducted in King Hussein Medical Hospital (KHMH) and analysis values were compared among the six tested ENFs groups by using ANOVA for continuous variables and Chi square test for nominal data after exclusion all hospitalized patients who were discharged or died before completed at least 1 week of dual enteral nutrition (EN) and TPN after admission.Results: The mean overall age was 58.4±9.9 years and 224 participants(68.7%) were male. The percentage changes in albumin level (%∆ALB) and other tested positive clinical and economic impacts were significantly highest in groups who were on ENFs with primarily high protein and caloric density (PD and CD) and were high or enriched with glutamine (GLT). Conclusion: In summary, using TF dose of ENFs in TPN dependent wasted hypoalbumenic hospitalized patients may have great positive clinical and economic outcomes especially if the ENF have a unique nutritional characteristic of higher PD, CD, and GLT, prebiotic, and zinc enrichments.
