Biological activities of the pulp of deutarium microcarpum fruit

Author: 
NGATCHIC METSAGANG Therese Josiane, FOMEKONG Guy Christian and NJINTANG YANOU Nicolas

Deutarium microcarpum is an edible wild fruit that has a high content of nutrients and bioactive compounds compared to that ofcertainsdomestic fruits. Inspiteits virtues, this fruit is still underexploited and undervalued by the nutraceutical industry due to little knowledge about it. The aim of this work is to study the biological properties of the pulp of Detarium microcarpum fruit. The bioactive coompounds and the in vitro antioxidant activity of the pulp of the fruit were determined. Different doses (250 mgg/kg, 500 mgg/kg and 750 mgg/kg) of pulp powder fruit was given to male rats during 28 days to evaluate the biological activities. At the end, hematological parameters, lipid properties and antioxidant activities were evaluated. Results show that the fruit is rich inphenolic compounds, such as flavonoids and tannins, in vitamin C and fibers. The levels of total cholesterol, LDL-cholesterol and triglyceride observed in animal groups taken fruit were lower than the control group. the most significant reduction was obtained with 750mg/kg dose p <0.05.Compared to control group, concentration of HDL-cholesterol in all animal groups taken fruit was significant higher p <0.05.The fruit also has a good antioxidant activity with an IC50 of 0.33 mg / mL and decreasing of malondialdehyde in all group rats taken fruit. These results show that the consumption of the pulp of Deutarium microcarpum fruit would be a good alternative for the treatment of diseases such as anemia, obesity, and oxidative stress.

Page: 
4697-4703
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DOI: 
http://dx.doi.org/10.24327/23956429.ijcmpr201911779
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