Ulcero-proliferative growth over extremities is common in day to day surgical life. The presenting complaints and time of presentation may vary through an ulcer, ulcero-proliferative growth, and fungating growths. Most commonly diagnosed in such ulcero-proliferative growth is squamous cell carcinoma diagnosed by edge-wedge biopsy and histopathological examination. Among the variants of squamous cell carcinoma, verrucous carcinoma is a rare variant. Verrucous carcinoma is a variant of well-differentiated squamous cell carcinoma. Verrucous carcinoma grows gradually, has a tendency of local invasion and seldom metastasizes. Verrucous carcinoma may occur in various head and neck locations, as well as in the genitalia. The oral cavity is the most common site of this tumor. Here we are presenting such a case of verrucous carcinoma over the leg (unusual site). Surgical resection with sufficient safety margin is recommended.
