Study of neonatal thrombocytopenia etiology, clinical profile, immediate outcome and short term follow up of neonatal thrombocytopenia

Amutha, J., Ramesh, S and Vinoth S

This study intends to find out various etiological factors, outcome, clinical manifestations, immediate outcome and short term follow up of surviving neonates presented  with thrombocytopenia in their neonatal period (<28days of life). In our study 186 neonates admitted in NICU of RMMCH, Chidambaram with thrombocytopenia were studied. The prevalence of thrombocytopenia in our study is 19.36%. The most common etiology in neonates with thrombocytopenia is septicemia (48.65%).  The most common clinical manifestation being respiratory distress (50%) followed by hemorrhagic manifestations (13.4%). In our study mortality rate is high among neonates who has thrombocytopenia associated with congenital malformations (4.8%). Neuro-developmental outcome of thrombocytopenic neonates in our study depends on associated features rather than severity of thrombocytopenia.

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