A study evaluating the current practices and trends for the use of amoxicillin-clavulanic acid along with other antimicrobials in dentistry

Mohammad Suhaib ,. Farida Ahmad and Mohd Ahmad

Introduction: Odontogenic infections are one of the most frequently encountered dental conditions which are managed primarily by surgical intervention along with antimicrobials.

Objective: The purpose of the study was to find out the current trend of Amoxicillin-Clavulanate prescription along with other antimicrobials and use of probiotics as cotherapy.

Methods: An Prescription based observational study was conducted on various facets like dental infections for which antimicrobial agents were prescribed, trend of Amoxycillin-Clavulanate along with other antimicrobial agents in dentistry.

Results: Out of 100 patients, males (54.0%) outnumbered females (42.0%). The most commonly reported dental infections for which antimicrobials were advised was Acute and Chronic periodontitis (48%), followed by Acute and Chronic gingivitis (32%), Caries (11%), Post RCT (4%), Pericoronitis (3%), Oral trauma (1%) and other condition (1%). Amoxicillin-Clavulanate (50%) followed by Ornidazole (21%), Ofloxacin (20%), Doxycycline (16%), Cefixime (9%) and Ciprofloxacin (3%), were used either as monotherapy or in combinations. Only two out of hundred patients were advised for culture & sensitivity tests to aid antimicrobial therapy. Two third of (74%) of patients completed the advised antibiotic therapy while 7 patients reported, nausea and vomiting as common adverse drug reactions (ADRs).

Conclusions: In the study, acute/chronic periodontal infections were reported as the most frequent condition for which antimicrobials were advised. Amoxicillin-Clavulunate emerged as the most widely used antimicrobial, and was prescribed in 51.5% of acute and 33% of chronic dental infections. A finding worth concern, was that the antimicrobials were prescribed without antibiotic sensitivity tests in most of the cases.7% patients reported ADR's.

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DOI: http://dx.doi.org/10.24327/23956429.ijcmpr20170129