Spontaneous membranous resealing after spontaneous preterm premature rupture of membranes

Objective: To detect spontaneous amniotic sealing rates after spontaneous preterm premature rupture of membranes (PPROM) between 20 and 34 weeks gestation and to describe the associated factors with resealing.
Material and Methods: Patients admitted due to PPROM between 20 and 34 weeks singleton gestation and followed in clinic are included in the study. Primary aim was to describe the spontaneous amniotic resealing rates after PPROM. Secondary aim was to describe the optimal latency time for resealing and obstetrical outcomes at resealed group.
Results: Total 114 patients are included in the study.16 of them were at prior to 24 weeks pregnancy during membrane rupture and 98 were between 24 and 34 weeks. Spontaneous resealing occurred at seven cases. All of them occurred in the first week after membrane rupture. The resealed group had longer durations of pregnancy and better neonatal outcomes.
Conclusion: Despite the great efforts to heal amniotic membranes after membrane rupture still there is no proven method primary to heal the membranes. Spontaneous resealing of membranes is the biggest advance of patients for better prognosis after PPROM.