Dental caries is a widely prevalent infectious disease afflicting the humans worldwide, second only to the common cold despite knowledge of most advanced sciences and technologies in dental practice. Medicinal plants have been documented for prevention and cure of many systemic diseases since ancient times. The application of natural products for the control of oral diseases is considered as an interesting alternative to synthetic antimicrobials due to their fewer side effects. Hence the search for alternative products continues and natural phyto-chemicals isolated from plants used in traditional medicine are considered as good alternatives to synthetic chemicals. This article brings an insight of known medicinal plants helpful in treatment of dental caries.