An observational clinical study to evaluate the impact of covid-19 and co-morbidities on patients of mucormycosis in cims hospital, bilaspur, chhattisgarh

Author: 
Ashutosh Kori., Arti Pandey., Suman Kumar Kujur., Richa Agrawal Gupta., Sachin Pandey and Chandrahas Dhruw

Background: Mucormycosis is an angio-invasive fungal infection due to fungi of the order Mucorales causes infection in humans only when the immunity is critically low, this is known to occur in patients with uncontrolled diabetes, post transplant and cancer. This fungus is normally present in environment. Diabetes mellitus (DM) is an independent risk factor for both severe COVID-19 and mucormycosis. The first case in Bilaspur was reported on 19th May 2021 during the peak of second wave of covid-19 in Bilaspur division. Objective: To evaluate the impact of covid-19 and co-morbidities on patients of mucormycosis in CIMS hospital, Bilaspur, Chhattisgarh. Method: This prospective observational clinical study is conducted in CIMS hospital Bilaspur, Chhattisgarh. The clinical data from mucormycosis (Black Fungus) ward during the covid-19 pandemic is collected, analyzed and studied. Result: The total IPD registered in CIMS hospital, mucormycosis ward is 36 till 15 June 2021. 10 out of 36 patients belonged to 18-45 years age group and 72.22% in >45 year age group. 63.88% patients were male whereas female patients were 13. 25 out of 36(65.44%) patients of lower socioeconomic status were registered in IPD, on the other hand 19.44% patients were of middle class economy status and only 11.11% were of upper class SES. 16 out of 36 patients were admitted with the chief complains of swelling over face out of these 27.77% patients had swelling over right side of face and rest were having that on left. Swelling over face was accompanied by dull pain which was seen in 21 patients. Swollen and black discoloration of eyes was observed in 11 patients out of that 8 were having diminished vision as well. 80.55% of admitted patients were having co-morbidities. 77.77% had Diabetes Mellitus type 2, 33.33% patients were chronic hypertensive, chronic kidney disease was found in 7 patients, 2 patients were having cardiac related problems and 3 were found to have hypothyroidism. 28 out of 36(77.77%) patients of mucormycosis had the history of covid-19 positivity and rest 22.22% patients did not have the covid-19 positive history. Conclusion: Majority of patients admitted in mucormycosis ward were old aged low SES male having multiple co-morbid conditions and with positive history of covid-19 infection. Painful swelling over face and eyes were seen predominately in most of the patients. Presence of Diabetes mellitus (DM) increased the risk of contracting mucormycosis and DM is associated with an increased severity of COVID-19 infection.

Page: 
5839-5842
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DOI: 
http://dx.doi.org/10.24327/23956429.ijcmpr20211026
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