In recent years, many ventricular repolarization markers on 12-derivation body surface ECGs have started to be used in various clinical conditions to predict malignant ventricular arrhythmias. Currently, QT dispersion is still the most commonly used evaluation method among these parameters. The failure to accurately identify the QRS complex and the T wave due to a variety of reasons has led to a search for different methods of assessing the repolarization period. However, the dispersion analyses of these new repolarization parameters failed to provide a more accurate diagnostic value than typical QT dispersion, and in some cases, it was not even found to be correlated with QT dispersion. Recent studies have shown that the Tp-e/QT ratio provides more accurate predictive data about ventricular arrhythmias than the measurement of QT, QTc, and the Tp-e interval and that it is not influenced by the variability of the heart rate. This review attempted to perform a thorough evaluation of the Tp-e/QT ratio that has started to be used more frequently in recent years.