Background: An evaluation of lung masses is often confusing radiographically or through conventional computed tomography. However, multidetector CT has provided a new ray of hope in diagnosing and differentiating malignant from benign cases. Methods: A total of 50 clinico-radiographically suspected cases of lung carcinoma were enrolled in the study. All the patients underwent a thorough clinical, radiographical and MDCT assessment. The MDCT findings were correlated with final diagnosis based on bronchoscopic/CT guided biopsy. Results: 37 (74%) cases were malignant (13 Sq CC, 5 Sm CC, 15 Adenocarcinoma and 4 others). Patient’s age ranged between 31 to 74 years with the mean age of 55.84 years. Majority were from rural areas (80%), males (70%) and smokers (76%), with Cough (92%), sputum (80%) and anorexia (72%) being the commonest symptoms. Pulmonary opacity (100%) and hilar enlargement (80%) were the most common radiographical findings. On MDCT, central location, mediastinal invasion, bone destruction, significant enhancement, spiculated/lobulated margins and metastatic signs were found to be significantly associated with malignancy. MDCT helped to differentiate among different malignant lesions. Conclusions: Multidetector computed tomography was found to have sensitivity, specificity, PPV, NPV and accuracy of 97.3%, 76.9%, 92.3%, 90.9% and 92.0% in detection of lung malignancy.
