Objective: To study lymphopenia as a marker in severity of COVID-19 disease Materials & methods: It is a retrospectiove observational study of the 64 COVID-19 cases admitted at a dedicated tertiary COVID hospital in Mumbai. We reported 64 COVID-19 cases presenting to our center with variable presentations. All the patients were evaluated with blood investigations, inflammatory markers and computed tomography of thorax on admission Results: The mean age of the study population was 54.93 years. Lymphopenia was noted in 34 number of cases and 45 patients had severe disease requiring oxygenation and intensive care. Total 8 patients died during the course of illness in the hospital. Out of the 8 patients died, 6 had absolute lymphopenia of less than 1000 cells/mm3 and out of that 6,4 cases had lymphopenia of less than 500 cells/mm3 Conclusion: Our study showed that lymphopeniawas associated with increased mortality, ARDS, need for ICU care, and severe COVID-19.Thus, lymphopenia can be useful to associate with the severity of the COVID-19 disease.
