Intrathecal isobaric 0.75% ropivacaine versus isobaric0.5% LEVOBUPIVACAINE – a double blinded randomized control study

Senthil Kumar V S and V Arun Pothan Raj

Background and objective: Toxicity of the earlier local anaesthetics was well known and the research for an alternative agent provided Ropivacaine and levobupivacaine. Our aim is to compare the onset, duration, sensory and motor blockade of intrathecal isobaric ropivacaine and isobaric levobupivacaine in inguinal hernia surgery
Materials and methods: After the approval of institutional ethical committee this randomized control trial was done between august and December 2014. A total of 50 patients were randomly allotted in two groups. R group received 3 ml of 0.75% Ropivacaine and L group received 3 ml of 0.5% Levobupivacaine. Duration and intensity of motor block was assessed by using modified Bromage scale and visual analogue scale was used to assess the duration of sensory block
Results: Analysis of the results showed that there was no significant difference in the onset of sensory block was 35.6±7.53 in R and 37.4±7.22 in L group and the onset of motor block between the two groups was 27.5±8.03 in R group and 25.54±10.01 in L group. The mean duration of sensory block was 212.1 ± 22.01 in R group and215.9 ± 22.38 in L group and the duration of motor block was145.7 ± 14.30 and 118.5 ± 10.61 in R and L group respectively. Both the values observed in the groups were clinically equal and statistically insignificant.
Conclusion: Both ropivacaine and levobupivacaine have equal efficacy in onset duration of sensory and motor block and also in the degree of motor block.


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