In 2009, a study investigated safety, efficacy and acceptability of praziquantel for the treatment of S. haematobium and S. mansoni infections among pre-school children in Hilat Daoud, Gezira State, Sudan. The study also investigated the burden of schistosomiasis and other health problems in this age group. The present follow up study was planned to investigate the overall health status of the children of Hilat Daoud. All the examined pre-school children (3-5 years old) were negative and there was no blood in all urine samples. The overall prevalence in the study area was 7.6 %. Anaemia and jaundice were not seen in these children; however, reducible umbilical hernia was detected in 11 children and hepatosplenomegaly in one child who was then referred to hospital for further evaluation. The health status of the children of Hilat Daoud has improved as a result of mass chemotherapy campaigns and awareness raising, however, access to safe drinking water, adequate sanitation, primary schools, health services and piped water supply remain the major problems of Hilat Daoud and other migrant communities. Ministries of health and Ministries of social welfare in all states in Sudan should make efforts to influence relevant policies targeting migrant agricultural workers and their families to promote the expansion of sanitation and clean water supply coverage and they should be included in all prevention and treatment campaigns.