Evaluation of thyroid hormone status in pregnancy induced hypertension

Vanathi R., Mallika A and Sangeereni M

Background and Objective: The objective of the study is to find the association between the thyroid hormone status with pregnancy induced hypertension.
Method: Thyroid hormones namely free tri-iodothyronine (FT3), free thyroxine (FT4), and Thyroid stimulating hormone (TSH) were evaluated at the time of diagnosis of PIH in 100 pregnant women.
Statistical Analysis: In the subjects, serum concentration of FT3, FT4 and TSH are estimated using immunoenzymometric assay. The demographic data and hormone levels were analysed using Pearson Chi-square test.
Results: Out of 100 participants 60% were primigravida and 40% were Multigravida. Mean age of the participants was 25.72±3.86 years. Statistics shows that 57% of participants contribute to euthyroid, 36% to subclinical hypothyroid, 5% to overt hypothyroid and 2% to overt hyperthyroid. There was a statistically significant association between PIH and thyroid hypofunction with P-value being 0.003.
Conclusion: In the present study a positive association was found between thyroid hypofunction and PIH which is statistically significant. With regards to the results of present study the measurement of serum levels of FT3, FT4, TSH can be suggested as a criterion for the prediction of PIH.

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DOI: http://dx.doi.org/10.24327/23956429.ijcmpr20170263
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