Epstein-barr virus is the cause of multiple sclerosis

Author: 
Ilija Barukčić

Aim: This systematic review assesses once again the causal relationship between Epstein-Barr virus (EBV) and multiple sclerosis (MS) for gaining a better understanding of the pathogenesis of this disease.
Methods: A systematic review and meat-analysis of some studies is provided aimed to answer among other questions the following question. Is there a cause effect relationship between Epstein-Barr virus and multiple sclerosis? The method of the conditio sine qua non relationship was used to proof the hypothesis without Epstein-Barr virus no multiple sclerosis. In other words, if multiple sclerosis is present, then Epstein-Barr virus is present too. The mathematical formula of the causal relationship k was used to proof the hypothesis, whether there is a cause effect relationship between Epstein-Barr virus and multiple sclerosis. Significance was indicated by a p-value of less than 0.05.
Results: The studies analysed were able to provide evidence that Epstein-Barr virus is a necessary condition (a conditio sine qua non) of multiple sclerosis. Furthermore, the studies analyzed provide impressive evidence of a cause-effect relationship between Epstein-Barr virus and multiple sclerosis.
Conclusion: Epstein-Barr virus the cause of multiple sclerosis.

Page: 
3674-3682
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DOI: 
http://dx.doi.org/10.24327/23956429.ijcmpr20180538
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