Efficacy of orange peel mouthwash against candida in diabetic patients

Author: 
Sheshaprasad., Ruchika.A.N and Anuradha Pai

Background: Diabetes mellitus is an endocrine disorder which increases susceptibility of an individual towards oral candidiasis. Chlorhexidine (CHX) is considered as a choice of treatment to prevent oral candidiasis but the long term use of chlorhexidine results into adverse effects. So, citrus aurantium (bitter orange) has been proved to be effective against candidiasisin many in-vitro studies and has no known side-effects. So, a study was undertaken to evaluate the efficacy of orange peel extract mouthwash in comparison to0.2% Chlorhexidine (CHX) mouth wash against oral candida albicans (CA) in type II diabetic patients.
Material and Method: 30 type-II diabetic patients are randomly divided into 2 groups of 15 patient search. Group 1-0.2% chlorhexidine mouthwash and Group 2- Orange peel extract mouthwash. Swab test was done before and after the use of respectivemouthwash in group 1 and group 2.
Results: CHX and Orange peel extract mouthwash were proved to be effective in decreasing the CA count, which is statistically significant (p > 0.05).When potency of both mouthwash were compared, there was no statistical significance noted. Hence, CHX is as effective as Orange Peel Extract mouthwash in decreasing CA colony count.
Conclusion: Orange peel extract mouthwash is found to be as effective as chlorhexidine mouthwash in reduction of CA count.

 

Page: 
3915-3917
Download PDF: 
DOI: 
http://dx.doi.org/10.24327/23956429.ijcmpr201812587
Select Volume: