Objective: CD is an inflammatory gastrointestinal tract disease that may involve extra intestinal systems. HS is a chronic inflammatory skin condition. Both disorders have poorly understood mechanism. A relation has been described in literature. Similarities in treatments and the way patients respond to them. We will discuss different aspects of disease presentation and available treatment modalities from available literature.
Design: A report of three cases.
Results: Two patients were diagnosed with CD first with complicated disease course. The third case was diagnosed with HS first. All had complicated HS course the required surgery. One patient failed one biological agent and responded to other. The second was treated with cytotoxic agents with acceptable results. No cytotoxic or biological agents were used on the third patient yet.
Conclusion: A possible relation between two conditions is likely based on several case reports and retrospective cohort, however, a prospective study is needed to establish the relation and to shed more light on treatment of both condition simultaneously. Both have an impact on patients' life styles; it is crucial to anticipate the correlation to provide the best treatment. Obstacles are likely to emerge due chronicity and delay in diagnosis.