Comparative study of the effect of the pretreatment with intravenous lignocaine and lignocaine with fentanyl and paracetamolon pain associated with injection of propofol after temporary venous occlusion

Author: 
Humane Josna, Jayashree Venkatesan, Humane Dhammdeep and Tirmale Rakesh

Background:Propofol is now most commonly used agent for induction of anaesthesia.

Objectives: To study incidence  and  severity  of pain using  Verbal  pain  rating scale by Mc Cirrick & Hunter and Face pain scale by Wong and Baker.

Methods and material:The study was conducted on two hundred adult patients with the American society of Anesthesiologists physical status  grade l and ll, scheduled for gynaecological, urological or general surgical procedures.A double blind randomized, placebo controlled study was carried out. Departmental and ethics committee permission obtained.

Results: Comparison of pain on propofol injection by verbal pain scale and face pain scale Post-Hoc test: multiple  comparision: Tukey test  when applied the difference is significant when VPS and FPS of control group is compared to lignocaine group ,lignocaine with fentanyl and paracetamol group , p value was <0.001.

Conclusion: Lignocaine 40 mg retained in tourniquet occluded vein for 60 seconds was effective in reducing propofol injection. Incidence of pain was less as compared to lignocaine 40 mg with fentanyl 100 mcg and paracetamol 1 mg/kg. Lignocaine 40 mg with fentanyl 100 mcg with venous occlusion was effective in reducing propofol injection pain. Paracetamol 1 mg/kg with venous occlusion was effective in reducing propofol injection pain.

Page: 
5947-5954
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DOI: 
http://dx.doi.org/10.24327/23956429.ijcmpr20211052
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