Cancer is one of the five main causes of death in all over the world. There are various ongoing studies in the field of oncology. One such advancement in oncology is the use of ascorbic acid as a chemotherapeutic agent. Recent studies claim that ascorbic acid is a potential chemotherapeutic agent. Studies show that vitamin C was preferentially toxic to tumor cells. High doses of intravenous ascorbates have shown positive results in complete remission of cancer using this modality. This article comments on such studies conducted in end stage cancer patients.