Hematidrosis is an exceptionally rare disease that was associated with religious beliefs, high blood pressure, menses, stress and systemic disease. This disease has been described as a stigmata, which is a term used by Christians to explain body marks, sores, pain, and bleeding in locations consistent with the crucifixion wounds of Jesus Christ. These wounds are typically on the hands, wrists, and feet. However, pathophysiology and etiology are still largely unknown. A complete patient’s medical and family history was obtained, physical examination and a detailed laboratory were conducted. A spectrum of autoimmune and oncological diseases were assayed. Ultrasounds, radiography, echocardiography, endoscopy, esophago-gastro-duodenoscopy were performed for final diagnosis. The patient’s past medical history were unremarkable. Physical examination was unexceptional for any abnormal findings. All of the labs were reported to be within normal limits. All the assays for autoimmune diseases were negative. The investigation at multiple facilities by pediatric nephrologists, hematologist-oncologists, immunologists, psychiatrists, and endocrinologists did not establish diagnosis. Bronchoscopy and gastroduodenal endoscopy were normal. The patient was discharged without diagnosis. After repeated bleedings a hematologist diagnosed this patient with hematidrosis. The diagnosis is consistent with this patient as she seemed to exhibit issues when she was stressed and her blood pressure increased.
